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Updated: Aug 14, 2025

Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles
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Advances in Lung Cancer Treatment Using Nanomedicines.

Akshansh Sharma1, Devanshi Shambhwani2, Sadanand Pandey3

  • 1Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan 173229, India.

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|January 16, 2023
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Summary

Nanotechnology offers new hope for lung cancer patients by improving drug delivery and enabling early detection. Nanoscale theranostic agents enhance treatment efficacy and reduce damage to healthy cells.

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Area of Science:

  • Oncology
  • Nanomedicine
  • Material Science

Background:

  • Lung carcinoma has a poor prognosis due to late detection and ineffective conventional treatments.
  • Nanoscale theranostic agents are emerging as promising tools to overcome these limitations.
  • These agents combine therapeutic delivery with diagnostic imaging capabilities.

Purpose of the Study:

  • To provide a comprehensive overview of nanocarrier-based theranostic agents for lung cancer.
  • To discuss overexpressed receptors in lung cancer relevant for targeted nanoparticle delivery.
  • To explore various targeting strategies employed by nanoparticles in lung cancer therapy.

Main Methods:

  • Review of current literature on nanotechnology in lung cancer treatment.
  • Analysis of different types of nanocarrier systems used for drug delivery.
  • Examination of targeting approaches for nanoparticles based on receptor expression.

Main Results:

  • Nanotechnology enhances bioavailability and stability of anti-cancer drugs.
  • Nanocarrier-based theranostics facilitate early detection and targeted drug delivery.
  • Various nanocarrier platforms like liposomes, nanoparticles, and micelles show therapeutic potential.

Conclusions:

  • Nanoscale theranostic agents represent a significant advancement in lung cancer management.
  • Targeted delivery systems can improve therapeutic outcomes and minimize side effects.
  • Further research into nanoparticle targeting and drug delivery is crucial for clinical application.