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Related Experiment Video

Updated: Aug 14, 2025

Oral Health Assessment by Lay Personnel for Older Adults
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Published on: February 2, 2020

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Periodontitis and low cognitive performance: A population-based study.

Crystal Marruganti1,2,3, Giacomo Baima4,5, Mario Aimetti4,5

  • 1Unit of Periodontology, Endodontology and Restorative Dentistry, Department of Medical Biotechnologies, University of Siena, Siena, Italy.

Journal of Clinical Periodontology
|January 16, 2023
PubMed
Summary
This summary is machine-generated.

Periodontitis, a gum disease, is linked to lower cognitive performance in older adults. This study found moderate to severe gum disease was associated with poorer performance on cognitive tests.

Keywords:
Alzheimer's diseasecognitive declinecognitive impairmentneurocognitive disordersperiodontal diseases

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Area of Science:

  • Gerontology
  • Epidemiology
  • Neuroscience

Background:

  • Periodontitis is a prevalent oral infection affecting older adults.
  • Cognitive decline is a significant concern in aging populations.
  • Potential links between oral health and cognitive function require further investigation.

Purpose of the Study:

  • To investigate the epidemiological association between periodontitis and cognitive performance in a U.S. older adult population.
  • To determine if periodontitis severity correlates with cognitive function deficits.

Main Methods:

  • Utilized data from 2086 older adults (≥60 years) from the NHANES 2011-2014 database.
  • Classified periodontitis severity (mild, moderate, severe) using AAP/CDC criteria.
  • Assessed cognitive function via CERAD, AFT, DSST, and global cognition scores, defining low performance as the lowest quartile.

Main Results:

  • Moderate and severe periodontitis showed significant associations with low Digit Symbol Substitution Test (DSST) performance.
  • Increased clinical attachment loss (CAL) correlated with lower performance in Animal Fluency Test (AFT), DSST, and global cognition.

Conclusions:

  • An independent association exists between periodontitis and reduced cognitive performance in older adults.
  • Periodontitis may represent a modifiable risk factor for cognitive impairment in aging individuals.