Related Experiment Video For Melanoma

Updated: Aug 14, 2025

Injection of Syngeneic Murine Melanoma Cells to Determine Their Metastatic Potential in the Lungs
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Injection of Syngeneic Murine Melanoma Cells to Determine Their Metastatic Potential in the Lungs

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Metastatic melanoma posing as a pelvic mass

Alexsaundra Zywicki1, Naixin Zhang2, Olivia Sagan3

  • 1Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY, USA.

Gynecologic Oncology Reports
|January 17, 2023
PubMed

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Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
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The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
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Keywords:
MelanomaMetastaticPelvic massRare