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Related Concept Videos

Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

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Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
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What is Monogastric Digestion?01:50

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The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
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Defense Against Bacterial Pathogens01:31

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The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
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Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
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Defense Mechanism Against Infection01:26

Defense Mechanism Against Infection

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Natural flora, body system defenses, and inflammation are natural barriers of the body against infectious agents regardless of previous exposure. Normal floras of the human body refer to the microbial population that colonizes the skin and mucous membranes.
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Surface Membrane Barriers01:18

Surface Membrane Barriers

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The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
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Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
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Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

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[Oral Microbiome and Systemic Diseases].

Lu-Jun Zhou1,2, Bo-Yan Chen1,2, Yu-Lin Li1,2

  • 1Laboratory of Oral Microbiota and Systemic Diseases, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Oral Diseases.

Sichuan Da Xue Xue Bao. Yi Xue Ban = Journal of Sichuan University. Medical Science Edition
|January 17, 2023
PubMed
Summary
This summary is machine-generated.

The oral microbiome, a diverse microbial community, impacts human health. Its imbalance is linked to systemic diseases, offering new diagnostic and treatment targets.

Keywords:
DysbiosisOral microbiomeSystemic diseases

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Area of Science:

  • Microbiology
  • Human Health
  • Oral Biology

Context:

  • The oral microbiome is a highly diverse microbial community crucial for human health.
  • Significant variations in microbial composition exist across oral cavity sites.
  • A dynamic equilibrium is maintained via host and environmental interactions.

Purpose:

  • To review recent research on the oral microbiome's connection to systemic health.
  • To explore the interactions and pathological mechanisms involved.
  • To identify new avenues for disease prevention and treatment.

Summary:

  • The oral microbiome plays a vital role in maintaining overall health.
  • Dysbiosis, or imbalance, in the oral microbiome correlates with various systemic diseases.
  • Understanding these links can lead to improved early detection and management strategies.

Impact:

  • Provides insights into the oral microbiome's role in systemic health.
  • Highlights the connection between oral health and overall well-being.
  • Suggests potential for novel therapeutic and diagnostic approaches targeting the oral microbiome.