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Updated: Aug 14, 2025

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Published on: January 22, 2020
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[Vitamins and Immune System Health]
Wei-Li Kong1, Xin-Rong Lu1, Lin-Lin Hou2
1Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.
Summary
Maintaining a healthy immune system is crucial for fighting infections. Vitamins A, B, C, D, and E play vital roles in immune regulation, and supplementation can enhance immunity and combat infections.
Area of Science:
- Nutrition and Immunology
- Biochemistry
- Infectious Disease Research
Context:
- Immune system health is vital for combating infections, influenced by diet and mental well-being.
- Vitamins are key dietary nutrients that actively regulate immune responses.
- Vitamin deficiency impairs immunity, often initiating in oral tissues, increasing susceptibility to pathogens.
Purpose:
- To review the immunomodulatory effects of vitamins A, B, C, D, and E.
- To highlight the role of vitamins in optimizing immune function and oral immunity.
- To propose an omics-based systemic approach for vitamin immune regulation research.
Summary:
- Vitamins are critical for immune function, with deficiencies leading to inflammation and reduced immunity.
- Supplementation can enhance immune defenses, offering a feasible anti-infection strategy.
- This review examines specific vitamins (A, B, C, D, E) and their impact on immunity.
Impact:
- Vitamin supplementation can optimize immune function and reduce infection susceptibility.
- An omics-based approach can overcome limitations of traditional single-factor research.
- Findings provide direction for basic and applied research in vitamin-mediated immune regulation and anti-infection strategies.
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