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Epidemiology of SARS-CoV-2 Omicron BA.5 Infections, Macau, June-July 2022

Weijia Xiong, Liping Peng, Tim K Tsang

    Emerging Infectious Diseases
    |January 17, 2023
    PubMed

    Insights

    A SARS-CoV-2 Omicron BA.5 outbreak in Macau resulted in over 1,800 mild cases and 6 deaths. Stringent public health measures, including universal testing and a 2-week stay-at-home order, successfully controlled the outbreak.

    Area of Science:

    • Epidemiology
    • Public Health
    • Infectious Disease Dynamics

    Background:

    • The SARS-CoV-2 Omicron BA.5 variant caused a significant outbreak in Macau between June and July 2022.
    • The outbreak involved over 1,800 laboratory-confirmed cases.

    Purpose of the Study:

    • To document the epidemiological characteristics of the SARS-CoV-2 Omicron BA.5 outbreak in Macau.
    • To evaluate the effectiveness of public health interventions in controlling the outbreak.

    Main Methods:

    • Retrospective analysis of laboratory-confirmed SARS-CoV-2 cases.
    • Description of implemented public health and social measures, including universal testing and stay-at-home orders.

    Main Results:

    • The majority of the >1,800 cases were mild or asymptomatic.
    • A low mortality rate was observed, with only 6 recorded deaths.
    • The outbreak was successfully contained within approximately 6 weeks.

    Conclusions:

    • Stringent public health and social measures were effective in controlling the SARS-CoV-2 Omicron BA.5 outbreak in Macau.
    • The variant predominantly caused mild disease, but swift control measures were crucial.
    • Lessons learned can inform future outbreak responses to emerging SARS-CoV-2 variants.
    Keywords:
    COVID-19MacauOmicron variantSARSSARS-CoV-2coronaviruscoronavirus diseaseincubation periodpublic healthreproductive numberrespiratory infectionssevere acute respiratory syndrome coronavirus 2social measuresviruseszoonoses

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