Related Experiment Video

Updated: Aug 14, 2025

Collecting And Measuring Wound Exudate Biochemical Mediators In Surgical Wounds
04:58

Collecting And Measuring Wound Exudate Biochemical Mediators In Surgical Wounds

Published on: October 20, 2012

12.1K

Microbial profile from peritoneal fluid and surgical wounds in patients with perforation peritonitis - A

Princy Gupta1, Pawanindra Lal1, Vikas Manchanda2

  • 1Department of Surgery, Lok Nayak Hospital, Delhi, India.

Tropical Doctor
|January 17, 2023
PubMed

Insights

Surgical site infections (SSIs) are common after perforation peritonitis. Cultures of peritoneal fluid and surgical wounds show consistent pathogens, justifying routine fluid cultures to guide antibiotic therapy.

Area of Science:

  • Infectious Diseases
  • Surgical Infections
  • Microbiology

Background:

  • Surgical site infection (SSI) is a significant complication following perforation peritonitis.
  • SSIs contribute to increased patient morbidity and mortality.

Purpose of the Study:

  • To investigate the consistency of microbial pathogens and their antibiotic sensitivity between intra-peritoneal fluid and post-operative wound cultures in patients with perforation peritonitis.
  • To determine if routine peritoneal fluid cultures can guide empirical antimicrobial therapy.

Main Methods:

  • Collected intra-peritoneal fluid and post-operative wound samples from patients undergoing surgery for perforation peritonitis.
  • Performed microbial culture and antibiotic sensitivity testing on all collected samples.
  • Compared the results of pathogen identification and sensitivity patterns between paired samples.

Main Results:

  • A high degree of consistency (80.6%) was observed in both the type of pathogen and its antibiotic sensitivity between intra-peritoneal fluid and post-operative wound cultures in 25 cases.
  • This consistency suggests that peritoneal fluid accurately reflects the microbial environment influencing wound infections.

Conclusions:

  • Routine culture and sensitivity testing of peritoneal fluid in cases of perforation peritonitis is clinically justified.
  • Adjusting empirical antimicrobial therapy based on peritoneal fluid culture results can optimize treatment and potentially reduce SSI rates.
Keywords:
Surgical site infectionemergency laparotomyperforation peritonitisperitoneal fluidroutine culture

More Related Videos

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections04:37

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections

Published on: February 2, 2024

898
Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis03:42

Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis

Published on: March 15, 2024

621

Related Concept Videos

Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
152
Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
123