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Updated: Aug 14, 2025

Determination of the Photoisomerization Quantum Yield of a Hydrazone Photoswitch
Published on: February 7, 2022
Multi-scene visual hydrazine hydrate detection based on a dibenzothiazole derivative
Yingshuang Chen1, Chuanfeng Zhao1, Xinyi Liu1
1Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, Jiangsu Key Laboratory of Bio-Functional Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, P. R. China. 07205@njnu.edu.cn.
Abstract:
Hydrazine (N2H4) produced by industries is distributed into different environments, and seriously threatens ecology and human security. Hence, it is important to develop probes that detect N2H4 in various environments. In this study, a novel N2H4 fluorescent probe was prepared based on a dibenzothiazole derivative (DBTD). The obtained DBTD probe demonstrated a strong ratio of colorimetric detection of N2H4, a rapid response, and good selectivity and sensitivity (detection limit 0.438 μM). Based on its good performance, the DBTD probe was successfully applied for the determination of trace N2H4 in water, cells, and zebrafish. In addition, the results of the fluorescence colocalization experiment demonstrated the lysosomal-targetable ability of DBTD.
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