Related Experiment Video
Updated: Aug 14, 2025

Author Spotlight: Enhancing In Vitro Cell Culture Models with Recombinant Functionalized Spider Silk Membranes
Published on: November 1, 2024
Biocompatible Optical Fibers Made of Regenerated Cellulose and Recombinant Cellulose-Binding Spider Silk
Martin Reimer1, Kai Mayer2, Daniel Van Opdenbosch1
1Chair for Biogenic Polymers, Technical University of Munich Campus Straubing for Biotechnology and Sustainability, Schulgasse 16, 94315 Straubing, Germany.
Abstract:
The fabrication of green optical waveguides based on cellulose and spider silk might allow the processing of novel biocompatible materials. Regenerated cellulose fibers are used as the core and recombinantly produced spider silk proteins eADF4(C16) as the cladding material. A detected delamination between core and cladding could be circumvented by using a modified spider silk protein with a cellulose-binding domain-enduring permanent adhesion between the cellulose core and the spider silk cladding. The applied spider silk materials were characterized optically, and the theoretical maximum data rate was determined. The results show optical waveguide structures promising for medical applications, for example, in the future.

