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Occurrence of Postoperative Delirium and the Use of Different Assessment Tools
Andrea Kirfel1, Diane Jossen1, Jan Menzenbach1
1Department of Anaesthesiology and Intensive Care Medicine, University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany.
Insights
Postoperative delirium (POD) is common in the first two days after surgery. While guidelines recommend assessment for five days, the highest incidence of POD occurs early, suggesting focused monitoring during this period.
Area of Science:
- Gerontology
- Critical Care Medicine
- Neuroscience
Background:
- Postoperative delirium (POD) significantly increases patient morbidity and healthcare costs.
- Standardized assessment and prevention strategies for POD are recommended by leading clinical guidelines.
- Early identification of POD is crucial for timely intervention and improved patient outcomes.
Purpose of the Study:
- To compare the efficacy of different delirium assessment tools in the postoperative period.
- To analyze the frequency and timing of POD development over the first five postoperative days.
- To evaluate the performance of the Confusion Assessment Method (CAM), 4 A's Test (4AT), and Delirium Observation Screening (DOS) scale.
Main Methods:
- Prospective observational study including 1097 patients at a university hospital.
- Utilized CAM-ICU/CAM, 4AT, and DOS scale for POD assessment over five consecutive postoperative days.
- Subgroup analysis from the PRe-Operative Prediction of Postoperative DElirium by Appropriate SCreening (PROPDESC) trial.
Main Results:
- The majority of new POD cases emerged on the first and second postoperative days.
- No single POD assessment tool demonstrated superior performance for definitive recommendation.
- POD occurrence peaked within the initial 48 hours post-surgery.
Conclusions:
- Postoperative delirium assessment is recommended for the first five days, with highest incidence in the first two days.
- Assessment tools incorporating direct patient questioning and observation are advisable.
- Further research may be needed to identify the optimal POD screening tool for clinical practice.
Abstract:
(1) Background: Postoperative delirium (POD) poses a high risk of worsening outcomes for patients and is also a burden for hospitals. The leading guidelines recommend standardized POD assessment and prevention. The aim of this subgroup analysis of the PRe-Operative Prediction of Postoperative DElirium by Appropriate SCreening (PROPDESC) trial was to compare different delirium assessments and to analyse the frequency of POD on five postoperative days. (2) Methods: This prospective observational trial enrolled 1097 patients in a university hospital from 2018 until 2019. The following POD assessment tools were used for five consecutive days: Confusion Assessment Method for ICU (CAM-ICU) or Confusion Assessment Method for normal ward (CAM), 4 A's Test (4AT) and Delirium Observation Screening (DOS) scale. (3) Results: In a 5-day visit interval, most new POD developments occurred on the first and second postoperative day. A clear recommendation for a specific POD assessment tool based on our results cannot be given. (4) Conclusions: According to guidelines, a POD assessment should take place on the first five postoperative days, but of these, the first two are those of highest POD occurrence. The POD assessment tool used should at best include direct patient questioning and aspects of patient observation.
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