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[Extraneural metastasis of an oligodendroglioma in ventriculo-peritoneal shunt]
Insights
This case report details a rare instance of oligodendroglioma with canalicular metastases in an infant. Despite surgical intervention and shunting, the patient succumbed to extensive local recurrence and widespread peritoneal metastasis.
Area of Science:
- Neuro-oncology
- Pediatric Pathology
- Neurosurgery
Context:
- Presents a rare case of oligodendroglioma in a seven-week-old infant.
- Highlights the challenges in managing pediatric brain tumors with obstructive hydrocephalus.
Purpose:
- To document and analyze an unusual presentation of oligodendroglioma with extensive metastatic spread.
- To contribute to the limited literature on canalicular metastases of glioma in pediatric patients.
Summary:
- A seven-week-old girl with signs of increased intracranial pressure (ICP) underwent shunt placement and later resection of an oligodendroglioma.
- The tumor recurred extensively, leading to death at 18 months, with autopsy revealing massive peritoneal metastases.
- This represents the eleventh reported case of canalicular metastases from a glioma.
Impact:
- Underscores the aggressive potential of pediatric oligodendrogliomas.
- Emphasizes the importance of considering rare metastatic patterns in neuro-oncology.
- Informs clinical management and prognostic considerations for similar pediatric cases.
Abstract:
The clinical and pathological report presents a seven-week old girl suffering from signs of raised ICP. A ventriculo-atrial shunt was inserted and replaced by a ventriculo-abdominal shunt due to occlusion at 15 months of age. At 16 months, craniotomy and resection of an oligodendroglioma was performed and the shunt was preserved. The child died at 18 months due to extensive local recurrence. Autopsy revealed massive peritoneal metastases of the tumor. This is the eleventh published case of canalicular metastases of glioma.