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Updated: Aug 14, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
A novel NIH research grant recommender using BERT
Jie Zhu1, Braja Gopal Patra2, Hulin Wu1
1Department of Biostatistics and Data Science, School of Public Health, The University of Texas Health Science Center, Houston, Texas, United States of America.
Abstract:
Research grants are important for researchers to sustain a good position in academia. There are many grant opportunities available from different funding agencies. However, finding relevant grant announcements is challenging and time-consuming for researchers. To resolve the problem, we proposed a grant announcements recommendation system for the National Institute of Health (NIH) grants using researchers' publications. We formulated the recommendation as a classification problem and proposed a recommender using state-of-the-art deep learning techniques: i.e. Bidirectional Encoder Representations from Transformers (BERT), to capture intrinsic, non-linear relationship between researchers' publications and grants announcements. Internal and external evaluations were conducted to assess the system's usefulness. During internal evaluations, the grant citations were used to establish grant-publication ground truth, and results were evaluated against Recall@k, Precision@k, Mean reciprocal rank (MRR) and Area under the Receiver Operating Characteristic curve (ROC-AUC). During external evaluations, researchers' publications were clustered using Dirichlet Process Mixture Model (DPMM), recommended grants by our model were then aggregated per cluster through Recency Weight, and finally researchers were invited to provide ratings to recommendations to calculate Precision@k. For comparison, baseline recommenders using Okapi Best Matching (BM25), Term-Frequency Inverse Document Frequency (TF-IDF), doc2vec, and Naïve Bayes (NB) were also developed. Both internal and external evaluations (all metrics) revealed favorable performances of our proposed BERT-based recommender.
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