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Clonic perseveration
1Westmead Hospital, Sydney, New South Wales.
Clinical and Experimental Neurology
|January 1, 1987
Summary
Clonic perseveration, a movement disorder, was observed in two patients after midbrain and thalamus infarction. This condition, potentially influenced by psychological factors, showed some voluntary control and could be induced by passive limb movements.
Area of Science:
- Neuroscience
- Neurology
- Movement Disorders
Background:
- Brain infarction can lead to various neurological deficits.
- Understanding the mechanisms of perseveration is crucial for diagnosis and treatment.
Observation:
- Two patients presented with clonic perseveration following infarction of the midbrain and thalamus.
- Perseveration manifested as involuntary, repetitive movements, affecting one or both sides of the body.
- In one patient, perseveration involved motor actions, drawing, writing, and speech.
Findings:
- Clonic perseveration was successfully induced by passive limb movements in both patients.
- The study suggests that clonic perseveration may be partially under voluntary control.
- This challenges previous assumptions about the lack of volitional influence in perseveration.
Implications:
- The findings highlight the potential underestimation of psychological factors in perseveration.
- Further research into the interplay of neurological damage and psychological influences is warranted.
- This study may inform novel therapeutic strategies for movement disorders involving perseveration.