Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

7.8K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
7.8K
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

5.0K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
5.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sequential Release of mRNA Complex and T Cells by a Double-Layered Implantable Scaffold for Combination Therapy of Head and Neck Squamous Cell Carcinoma.

International journal of nanomedicine·2026
Same author

Current Advancements in the Arsenal for Spinal Cord Injury Repair: Novel Drug Formulations.

International journal of nanomedicine·2026
Same author

Hydrogels for Cancer Immunotherapy: Strategies From Construction to Application.

MedComm·2026
Same author

An Implantable Double-Layered Spherical Scaffold Depositing Gene and Cell Agents to Facilitate Collaborative Cancer Immunotherapy.

ACS nano·2025
Same author

Chimeric Antigen Receptor-Engineered Cell Membrane-Coated Nanoparticles Promote Dual-Targeted mRNA-Based Cancer Gene Therapy.

ACS nano·2025
Same author

A Novel Systemic siDR6 Delivery System Based on DP7-C for the Treatment of Metastatic Lung Cancer.

International journal of nanomedicine·2025
Same journal

Epilepsy: Epidemiology, Molecular Pathogenesis, and Clinical Management.

MedComm·2026
Same journal

Metabolic Dysfunction-Associated Fatty Liver Disease: From Pathogenesis to Treatment.

MedComm·2026
Same journal

Dexmedetomidine Rapidly Relieves Stress-Induced Hyperalgesia via Presynaptic <i>α</i>2-Adrenergic Inhibition at Orbitofrontal-Insular Glutamatergic Synapses.

MedComm·2026
Same journal

Osteoarthritis: Epidemiology, Diagnosis, and Treatment.

MedComm·2026
Same journal

Multiomics Identification and Validation of an Integrin-Extracellular Matrix Network Driving Respiratory Syncytial Virus-Induced Lung Injury and Repair.

MedComm·2026
Same journal

A Low Serum Calcium-to-Potassium Ratio Predicts Postpartum Venous Thromboembolism Risk: Mediation by Hemoglobin and D-Dimer in a Multicenter Cohort.

MedComm·2026
See all related articles

Related Experiment Video

Updated: Aug 14, 2025

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
09:01

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy

Published on: May 22, 2020

3.2K

Multifunctional nanoparticle for cancer therapy.

Yan Gao1, Kaiyu Wang1, Jin Zhang1

  • 1State Key Laboratory of Biotherapy and Cancer Center West China Hospital of Sichuan University Chengdu Sichuan Province China.

Medcomm
|January 19, 2023
PubMed
Summary
This summary is machine-generated.

Multifunctional nanoparticles offer potent cancer therapy by integrating multiple tumor-targeting functions. This review details their construction strategies and application advances for improved cancer treatment.

Keywords:
backbonecancermodificationmultifunctional nanoparticles

More Related Videos

Author Spotlight: Innovative Cancer Therapies with Iron Oxide Nanoparticles for Glioblastoma Treatment
09:02

Author Spotlight: Innovative Cancer Therapies with Iron Oxide Nanoparticles for Glioblastoma Treatment

Published on: September 27, 2024

2.7K
Biofunctionalization of Magnetic Nanomaterials
06:40

Biofunctionalization of Magnetic Nanomaterials

Published on: July 16, 2020

2.7K

Related Experiment Videos

Last Updated: Aug 14, 2025

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
09:01

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy

Published on: May 22, 2020

3.2K
Author Spotlight: Innovative Cancer Therapies with Iron Oxide Nanoparticles for Glioblastoma Treatment
09:02

Author Spotlight: Innovative Cancer Therapies with Iron Oxide Nanoparticles for Glioblastoma Treatment

Published on: September 27, 2024

2.7K
Biofunctionalization of Magnetic Nanomaterials
06:40

Biofunctionalization of Magnetic Nanomaterials

Published on: July 16, 2020

2.7K

Area of Science:

  • Nanotechnology
  • Oncology
  • Materials Science

Background:

  • Cancer is a complex, multi-system disease requiring targeted therapies.
  • Nanotechnology offers advanced nanocarriers for effective cancer treatment.
  • Multifunctional nanoparticles show enhanced potency compared to single-function counterparts.

Purpose of the Study:

  • To systematically review the construction strategies of multifunctional nanoparticles.
  • To analyze recent advances in the application of these nanoparticles in cancer therapy.
  • To provide a comprehensive understanding of their design and functionalization.

Main Methods:

  • Systematic generalization of platform structures (organic/inorganic backbones).
  • Emphasis on functionalization and modification strategies for enhanced capabilities.
  • Discussion of application combination strategies for synergistic effects.

Main Results:

  • Overview of diverse multifunctional nanoparticle architectures.
  • Detailed analysis of functionalization techniques for improved targeting and efficacy.
  • Exploration of combined therapeutic strategies for enhanced anti-cancer outcomes.

Conclusions:

  • Multifunctional nanoparticles represent a sophisticated approach to cancer therapy.
  • Effective design requires careful consideration of backbone, modification, preparation, and integration.
  • Recent advances highlight their significant therapeutic potential and future directions.