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Published on: May 7, 2020
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Drug-induced aseptic meningitis
Camilla Ågnes1, Thomas Schwartz2, Else Quist-Paulsen3
1Indremedisinsk avdeling, og, Enhet for indremedisinsk forskning, Medisinsk klinikk, Oslo universitetssykehus, Ullevål sykehus.
Summary
Drug-induced aseptic meningitis is a rare condition. Suspect it in patients with meningitis symptoms and negative microbiological tests, especially after drug exposure.
Area of Science:
- Neurology
- Infectious Diseases
- Pharmacology
Background:
- Drug-induced aseptic meningitis is a rare but serious adverse drug reaction.
- It presents with meningitis symptoms but lacks microbiological evidence of infection.
- Recurrent urinary tract infections can lead to repeated exposure to certain medications.
Purpose of the Study:
- To highlight the importance of considering drug-induced aseptic meningitis in differential diagnosis.
- To present a case study of a patient with recurrent meningitis symptoms linked to drug exposure.
- To emphasize the need for thorough medical history in diagnosing aseptic meningitis.
Main Methods:
- Case report presentation.
- Review of patient's medical history, focusing on drug exposure and symptom onset.
- Differential diagnosis process for meningitis.
Main Results:
- The patient presented with recurrent meningitis symptoms.
- Symptoms resolved upon discontinuation of the suspected drug and recurred upon re-exposure.
- Microbiological tests for meningitis were consistently negative.
Conclusions:
- Drug-induced aseptic meningitis should be suspected in cases of unexplained meningitis, particularly with negative infectious workups.
- A detailed drug history is crucial for diagnosing this condition.
- Prompt recognition and drug withdrawal can lead to favorable outcomes.
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