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Bactericidal and antineoplastic effect of combination of norfloxacin and adriamycin
M Castelli1, M L Barbieri, A Bertolini
1Department of Pharmacology, Chemotherapy and Toxicology, University of Milano, Italy.
Chemotherapy
|January 1, 1987
Abstract:
Norfloxacin and adriamycin were tested alone and in combination for bactericidal activity against different strains of gram-negative bacteria. The antitumoral effect of a combination of norfloxacin and adriamycin was determined in mice bearing Ehrlich ascites carcinoma and in mice bearing P 388 leukemia. No interference with the antibacterial activity of norfloxacin or with the antitumoral activity of adriamycin was observed.