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Updated: Aug 13, 2025

Scalable Biomanufacturing Workflow to Produce and Isolate Natural Killer Cell-Derived Extracellular Vesicle-Based Cancer Biotherapeutics
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Efficient cell death mediated by bioengineered killer extracellular vesicles.

Julia Dancourt1, Ester Piovesana2, Gregory Lavieu3

  • 1Université Paris Cité, INSERM U1316, UMR 7057/CNRS, Paris, France. julia.dancourt@ext.inserm.fr.

Scientific Reports
|January 19, 2023
PubMed
Summary

Engineered extracellular vesicles (EVs) carrying diphtheria toxin kill cancer cells by blocking protein synthesis. This novel therapeutic approach shows promise for in vivo tumor ablation and cancer treatment.

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