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The Singapore National Precision Medicine Strategy
Eleanor Wong1, Nicolas Bertin1, Maxime Hebrard1
1Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.
Nature Genetics
|January 19, 2023
Summary
Precision medicine advances healthcare through personalized treatments. Singapore
Area of Science:
- Genomics
- Personalized Medicine
- Public Health
Background:
- Precision medicine offers transformative potential for healthcare.
- Genomic-phenotypic database analysis is key to precision medicine.
- Under-representation of Asian ancestries in databases limits discovery.
Purpose of the Study:
- To highlight the importance of diverse genomic data for precision medicine.
- To introduce the Singapore National Precision Medicine initiative.
- To address barriers to clinical adoption of precision medicine.
Main Methods:
- Generating large-scale, integrated genomic, lifestyle, health, social, and environmental data.
- Focusing on a whole-of-government, 10-year initiative.
- Analyzing health economic factors and identifying driver use cases.
Main Results:
- The Singapore National Precision Medicine initiative aims to collect data from up to one million individuals.
- Addressing social, ethical, legal, and regulatory barriers is crucial for adoption.
- Demonstrating value-based healthcare through health economics is vital.
Conclusions:
- Expanding genomic databases to include under-represented populations is essential.
- The Singapore initiative represents a significant step towards equitable precision medicine.
- Overcoming implementation barriers is necessary for widespread clinical integration.
