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Updated: Aug 13, 2025

Author Spotlight: Neutrophil Extracellular Traps Imaging in Human and Mouse Tissues
Published on: August 18, 2023
Neutrophil extracellular traps and pulmonary fibrosis: an update
Suyan Yan1, Meiqi Li1, Baocheng Liu1
1Department of Rheumatology and Immunology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No. 324, Jingwu Road, Huaiyin District, Jinan, 250021, Shandong, China.
Abstract:
Pulmonary fibrosis (PF) is a serious and often fatal illness that occurs in various clinical settings and represents a significant unmet medical need. Increasing evidence indicates that neutrophil extracellular traps (NETs) contribute significantly to the progression of PF. Therefore, understanding the pathways by which NETs contribute to the disease is crucial for developing effective treatments. This review focuses on the formation of NETs and the common mechanisms of NETs in PF.
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