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Related Experiment Videos

Imaging in plague.

A J Moreno1, T A Reeves, A A Rodriguez

  • 1Department of Medicine, William Beaumont Army Medical Center, El Paso, TX 79920-5001.

European Journal of Nuclear Medicine
|January 1, 1987
PubMed
Summary
This summary is machine-generated.

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A rare pediatric case of Yersinia pestis septic shock was successfully treated with antibiotics. Relapse was detected using Gallium-67 scintigraphy, highlighting its utility in diagnosing persistent plague infections.

Area of Science:

  • Pediatric Infectious Diseases
  • Medical Imaging
  • Microbiology

Background:

  • Yersinia pestis infection, or plague, is a serious bacterial disease.
  • Septic shock is a life-threatening condition caused by severe infection.
  • Pediatric plague cases are rare and can present with diverse symptoms.

Observation:

  • An 8-year-old boy presented with symptoms including fever, malaise, hepatosplenomegaly, mesenteric adenitis, and septic shock.
  • Blood and lymph node cultures confirmed Yersinia pestis.
  • The patient relapsed after initial antibiotic treatment, with symptoms of fever and abdominal pain.

Findings:

  • Gallium-67 citrate scintigraphy revealed abnormal radiopharmaceutical uptake in necrosed lymph nodes and the left hip region.

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  • 111In-labeled leukocytes imaging did not show abnormalities.
  • Computed tomography (CT) was used for correlative imaging.

    • Implications:

    • Gallium-67 scintigraphy can be a valuable tool for diagnosing plague recurrence or persistent infection, especially when other imaging modalities are inconclusive.
    • Early and accurate diagnosis and treatment are crucial for managing pediatric plague.
    • This case underscores the importance of considering rare infectious agents in severe pediatric illnesses.