Related Experiment Video
Updated: Aug 13, 2025

Micro-Computed Tomography Analysis of the Knee in Aged Dunkin-Hartley Guinea Pigs after Intra Articular Injection
Published on: August 2, 2024
Localized Pigmented Villonodular Synovitis of the Bilateral Knee: A Case Report
Hiroki Okamura1, Hiroki Ishikawa1, Takuya Ohno1
1Department of Orthopedic Surgery, Nihon Koukan Hospital, 1-2-1 Koukandori, Kawasaki-ku, Kanagawa, Japan.
Introduction:
Localized pigmented villonodular synovitis (PVNS) is a rare and benign condition of synovial tissue proliferation that affects the joints, tendon sheaths, and bursae. This case report is the first to describe a patient with a diagnosis of localized PVNS of the knee after presentation with bilateral and simultaneous onset of associated knee pain.
Case Report:
A 28-year-old Japanese woman presented to our hospital with a 1-year history of bilateral knee pain and right knee locking that started 1 month ago. Magnetic resonance imaging demonstrated a mass lesion in both the anterior compartment of the right knee and in the posterior compartments of the left knee. Arthroscopic resection of the lesions was performed, and the diagnosis of localized PVNS was made by pathological analysis. At the 6-month follow-up, no evidence of recurrence was noted.
Conclusion:
This case report describes localized PVNS of the bilateral knee, which is extremely rare. PVNS is a disease requiring surgical resection and should not be overlooked. It should be treated with the possibility of bilateral occurrence in mind.
More Related Videos
07:15In vivo Macrophage Imaging Using MR Targeted Contrast Agent for Longitudinal Evaluation of Septic Arthritis
Published on: October 20, 2013
14:49Clinical Protocol of Producing Adipose Tissue-Derived Stromal Vascular Fraction for Potential Cartilage Regeneration
Published on: September 29, 2018
Related Concept Videos
Nephrotic Syndrome I : Introduction
Knee Joint
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
Acute Pyelonephritis II: Diagnostic Studies and Management
Nephrotic Syndrome II : Assessment and Medical Management
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation