The Burden of Sickle Cell Disease in Saudi Arabia: A Single-Institution Large Retrospective Study

Amerah Bin Zuair1, Sheikhah Aldossari1, Rand Alhumaidi1

  • 1Department of Internal Medicine, College of Medicine, King Saud University and King Saud University Medical City, Riyadh, Saudi Arabia.

Insights

Sickle cell disease (SCD) patients experience frequent hospital admissions and high readmission rates, impacting quality of life and healthcare costs. Specialized multidisciplinary clinics are recommended to manage SCD effectively.

Area of Science:

  • Internal Medicine
  • Hematology
  • Public Health

Background:

  • Sickle cell disease (SCD) presents a substantial challenge to patients and healthcare systems.
  • High readmission rates are a significant factor contributing to the burden of SCD.

Purpose of the Study:

  • To characterize adult SCD patients admitted to General Internal Medicine.
  • To determine the etiology of admissions, annual admission rates, length of stay, and readmission rates for SCD patients.

Main Methods:

  • Retrospective observational study design.
  • Inclusion of all adult SCD patients admitted to the General Internal Medicine (GIM) unit from 2016 to 2021.

Main Results:

  • 160 adult SCD patients were analyzed (mean age 31.08 years, 51.25% female).
  • Average annual emergency department (ED) visits were 4, with 19% having ≥3 admissions.
  • Mean length of stay was 6 days; 30-day readmission rate was 24.5%.

Conclusions:

  • SCD imposes a significant economic and healthcare burden in Saudi Arabia.
  • High ED visits, readmission rates, and prolonged hospitalizations highlight the need for improved care.
  • Implementation of specialized sickle cell disease multidisciplinary clinics is advocated.
Abstract

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