Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Conduction System of the Heart01:19

Conduction System of the Heart

9.5K
Autorhythmicity is a term that refers to the heart's inherent ability to generate electrical signals and instigate muscle contractions. This self-regulating conduction system within the heart consists of two key components: the pacemaker cells and specialized conducting cells.
The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...
9.5K
Conduction01:20

Conduction

1
ConductionConduction is the heat transfer process through direct contact between particles without the movement of the substance itself. It occurs in solids, liquids, and gases, but is most effective in solids, particularly metals, due to their tightly packed particles and free-moving electrons. Conduction is vital daily, from cooking food on a stove to building insulation.Science and Engineering Practices (SEP): Analyzing and Interpreting DataScientists study conduction by analyzing different...
1
Dysrhythmias IV: Characteristics of Bradyarrhythmias01:18

Dysrhythmias IV: Characteristics of Bradyarrhythmias

17
Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
17
Electrophysiology of Normal Cardiac Rhythm01:19

Electrophysiology of Normal Cardiac Rhythm

6.7K
The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase...
6.7K
Electrocardiogram Fundamentals01:28

Electrocardiogram Fundamentals

682
Introduction
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
682
The Cardiac Cycle01:13

The Cardiac Cycle

89.6K
The heart beats rhythmically in a sequence called the cardiac cycle—a rapid coordination of contraction (systole) and relaxation (diastole).
The Process
Electrical signals—sent from the sinoatrial (SA) node in the right atrial wall to the atrioventricular (AV) node between the right atrium and right ventricle—cause both atria to simultaneously contract. When the signal reaches the AV node, it pauses for approximately a tenth of a second, allowing the atria to contract and...
89.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Authors' response to commentary on "Echocardiographic phenotypes in sepsis: identifying subgroups using latent profile analysis".

Journal of intensive care·2026
Same author

Cardio Heart Connect: Protocol for a Randomized Trial of a Commercially Available mHealth Fitness Intervention for Cardiac Rehabilitation After Transcatheter Aortic Valve Replacement.

medRxiv : the preprint server for health sciences·2026
Same author

The FUEL FALD Study: Effects of Udenafil on Liver Stiffness and Fibrosis after Fontan.

Pediatric cardiology·2026
Same author

Impact of adjunctive posterior left atrial ablation using pulsed field ablation on health care utilization in patients receiving first-time catheter ablation for atrial fibrillation: Results from the multicenter SENTINEL registry.

Heart rhythm·2026
Same author

Peak QRS/T ratio and the spatial ventricular gradient differentiate acute vs chronic left bundle branch block after transcatheter aortic valve replacement.

Heart rhythm O2·2026
Same author

Cardiometabolic health and the timing of habitual exercise in the All of Us Research Program.

medRxiv : the preprint server for health sciences·2026

Related Experiment Video

Updated: Aug 13, 2025

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

10.5K

Conduction system pacing learning curve: Left bundle pacing compared to His bundle pacing.

Matthew O'Connor1,2, Rui Shi1, Daniel B Kramer1,3

  • 1Heart Rhythm Centre, The Royal Brompton and Harefield NHS Foundation Trust, Guys & St Thomas' NHS Foundation Trust, UK.

International Journal of Cardiology. Heart & Vasculature
|January 20, 2023
PubMed
Summary
This summary is machine-generated.

Left bundle branch area pacing (LBBAP) demonstrated a shorter learning curve than His bundle pacing (HBP) for conduction system pacing (CSP). LBBAP procedural times plateaued after 10 cases, suggesting easier implementation for new centers.

Keywords:
Conduction system pacingHis bundle pacingLearning curveLeft bundle branch area pacingLeft bundle pacing

More Related Videos

Optocardiography and Electrophysiology Studies of Ex Vivo Langendorff-perfused Hearts
09:52

Optocardiography and Electrophysiology Studies of Ex Vivo Langendorff-perfused Hearts

Published on: November 7, 2019

13.1K
Translational Rabbit Model of Chronic Cardiac Pacing
06:14

Translational Rabbit Model of Chronic Cardiac Pacing

Published on: January 6, 2023

2.7K

Related Experiment Videos

Last Updated: Aug 13, 2025

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

10.5K
Optocardiography and Electrophysiology Studies of Ex Vivo Langendorff-perfused Hearts
09:52

Optocardiography and Electrophysiology Studies of Ex Vivo Langendorff-perfused Hearts

Published on: November 7, 2019

13.1K
Translational Rabbit Model of Chronic Cardiac Pacing
06:14

Translational Rabbit Model of Chronic Cardiac Pacing

Published on: January 6, 2023

2.7K

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Conduction system pacing (CSP) offers single lead left ventricular resynchronization.
  • His bundle pacing (HBP) and left bundle branch area pacing (LBBAP) are key CSP techniques.
  • Understanding the learning curve is crucial for new implanters and centers.

Purpose of the Study:

  • To compare the learning curves of HBP and LBBAP.
  • To evaluate procedural duration and fluoroscopy time as surrogates for learning curves.
  • To assess the feasibility of establishing CSP programs with LBBAP versus HBP.

Main Methods:

  • Retrospective review of the first 30 HBP and 30 LBBAP cases.
  • Analysis of procedural duration and fluoroscopy time.
  • Comparison of patient characteristics including LV ejection fraction and QRS duration.

Main Results:

  • Patient characteristics were similar between HBP and LBBAP groups.
  • Mean procedural duration was significantly shorter for LBBAP (87 min) than HBP (107 min).
  • Fluoroscopic screening time was also significantly shorter for LBBAP (8 min) compared to HBP (16 min).

Conclusions:

  • LBBAP exhibits a shorter learning curve, plateauing after approximately 10 cases.
  • HBP shows a longer learning curve with continued improvement over 30 cases.
  • LBBAP may facilitate easier establishment of CSP programs due to its shorter learning curve and superior parameters.