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A 'needle in a haystack': Drug-induced thrombotic thrombocytopenic purpura-Association or causality?
1Department of Haematology and National Institute for Health Research Cardiometabolic Programme, Haematology BRC, University College London Hospital/University College London, London, UK.
Abstract:
The risk of a drug associated with thrombotic thrombocytopenic purpura (TTP) demonstrating causality is rare, but it is important to keep an open mind of possible associations. Use of criteria to ascertain causality of drugs that may be related to thrombotic microangiopathies and exclude TTP, may be a useful resource. Commentary on: Schofield et al. Drug-induced thrombotic thrombocytopenic purpura: A systematic review and review of European and North American pharmacovigilance data. Br J Haematol 2023;200:766-773.
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