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Arteriovenous hemofiltration in children with multiple organ system failure
The International Journal of Artificial Organs
|July 1, 1987
Summary
Continuous arteriovenous hemofiltration (CAVH) effectively treated critically ill children with multiple organ system failure (MOSF). This renal replacement therapy managed fluid, electrolytes, and azotemia, potentially improving survival rates.
Area of Science:
- Pediatric Critical Care Medicine
- Nephrology
- Extracorporeal Therapies
Background:
- Critically ill children often experience multiple organ system failure (MOSF).
- Managing fluid, electrolyte, and acid-base balance is crucial in these patients.
- Continuous arteriovenous hemofiltration (CAVH) is an extracorporeal therapy.
Purpose of the Study:
- To evaluate the efficacy of CAVH in critically ill children with MOSF.
- To assess CAVH's impact on azotemia, fluid, and electrolyte balance.
- To determine CAVH's potential role in improving survival rates.
Main Methods:
- Nine critically ill children with MOSF were treated with CAVH.
- Treatment duration averaged 136 hours.
- Ultrafiltration rates and caloric intake were monitored.
Main Results:
- CAVH rapidly corrected hypervolemia and pulmonary edema.
- Mean serum creatinine levels were managed effectively.
- High ultrafiltration rates facilitated medication delivery.
Conclusions:
- CAVH is an effective renal replacement system for critically ill children with MOSF.
- It helps control azotemia, fluid, and acid-base status.
- CAVH may improve survival in pediatric patients with MOSF.