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Bilateral posterior choanal atresia: a morphologic and histologic study, and computed tomographic correlation
O E Brown1, D K Burns, T H Smith
1Department of Otorhinolaryngology, University of Texas Health Science Center at Dallas 75235.
International Journal of Pediatric Otorhinolaryngology
|August 1, 1987
Summary
Bilateral posterior choanal atresia, a rare newborn breathing obstruction, has its histopathology detailed. Computed tomography (CT) accurately identifies these abnormalities, aiding diagnosis.
Area of Science:
- Otolaryngology
- Pediatric Radiology
- Medical Histopathology
Background:
- Bilateral posterior choanal atresia is an uncommon cause of neonatal respiratory distress.
- While clinical aspects and treatments are known, histopathological details remain scarce.
- Correlation between radiologic findings and histopathology has been limited.
Observation:
- Two neonates with CHARGE association and bilateral posterior choanal atresia were evaluated.
- Computed tomography (CT) was used for radiologic assessment.
- Atretic tissue was examined macroscopically and microscopically after autopsy.
Findings:
- CT scans accurately depicted the histopathologic features of choanal atresia.
- Detailed histopathology of the atresia plates was described.
- The study established a correlation between CT imaging and underlying tissue abnormalities.
Implications:
- CT is a valuable tool for defining the histopathology of bilateral posterior choanal atresia.
- Enhanced understanding of histopathology can refine diagnostic accuracy.
- This correlation may improve management strategies for affected newborns.