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From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

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Effect of Post-Polyketide Synthase Modification Groups on Property and Activity of Polyene Macrolides

Liqin Qiao1, Yao Dong2, Hongli Zhou1,3

  • 1School of Chemistry and Pharmaceutical Engineering, Jilin Institute of Chemical Technology, Jilin 132022, China.

Antibiotics (Basel, Switzerland)
|January 21, 2023
PubMed

Keywords:
antifungal activitypolyene macrolidespost-PKS modificationsproperty

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