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Coumarin Triazoles as Potential Antimicrobial Agents
Siddappa A Patil1, Aravind R Nesaragi1, Raúl R Rodríguez-Berrios2
1Centre for Nano and Material Sciences, Jain University, Jain Global Campus, Bangalore 562112, Karnataka, India.
Antibiotics (Basel, Switzerland)
|January 21, 2023
Summary
Antibiotic resistance is a growing global health threat. Coumarin triazole derivatives show promise as novel antimicrobial agents, offering potential alternatives to combat resistant microbial infections.
Area of Science:
- Medicinal Chemistry
- Drug Discovery
- Antimicrobial Agents
Background:
- Microbial infections are a leading cause of death worldwide.
- Increasing antibiotic resistance necessitates the search for novel antimicrobial agents.
- Coumarin derivatives possess diverse therapeutic properties, including antimicrobial activity.
Purpose of the Study:
- To review recent advances in coumarin triazole derivatives as potential antimicrobial agents.
- To highlight their therapeutic applications against microbial infections.
- To cover literature published between 2006 and 2022.
Main Methods:
- Literature review of scientific articles.
- Analysis of coumarin triazole derivatives' synthesis and biological activities.
- Focus on antimicrobial properties.
Main Results:
- Coumarin triazole derivatives exhibit significant antimicrobial potential.
- These compounds show promise in combating various microbial infections.
- The review covers a substantial body of research from 2006-2022.
Conclusions:
- Coumarin triazole derivatives represent a promising class of compounds for developing new antimicrobial therapies.
- Further research is warranted to explore their full therapeutic potential.
- These derivatives could offer viable alternatives to address antibiotic resistance.
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