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Noninvasive Electrocardiography in the Perinatal Mouse
Published on: June 12, 2020
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Unsupervised Learning-Based Non-Invasive Fetal ECG Muti-Level Signal Quality Assessment
Xintong Shi1, Kohei Yamamoto2, Tomoaki Ohtsuki2
1Graduate School of Science and Technology, Keio University, Yokohama 223-8522, Japan.
Bioengineering (Basel, Switzerland)
|January 21, 2023
Summary
This study introduces an unsupervised method to assess fetal electrocardiogram (ECG) signal quality, improving fetal heart rate estimation accuracy. The approach effectively classifies signals into three quality levels, reducing errors in monitoring fetal health.
Area of Science:
- Biomedical Engineering
- Signal Processing
- Maternal-Fetal Medicine
Background:
- Fetal heart rate (FHR) monitoring is crucial for assessing fetal health and growth.
- Non-invasive fetal electrocardiogram (fECG) is widely used for FHR estimation but is susceptible to noise, compromising accuracy.
- Accurate FHR estimation requires reliable fECG signal quality assessment (SQA) to remove low-quality segments.
Purpose of the Study:
- To develop an unsupervised learning-based multi-level fECG SQA approach.
- To classify fECG signal segments into three quality levels (high, medium, low).
- To improve the accuracy of FHR estimation by removing low-quality fECG data.
Main Methods:
- Extracted signal quality features: entropy-based, statistical, and ECG signal quality indices.
- Calculated autoencoder-based features using reconstruction error of spectrograms.
- Classified fECG signal quality using a self-organizing map with extracted features.
Main Results:
- Achieved a weighted average F1-score of 90% for three-level fECG signal quality classification.
- Demonstrated a reduction in FHR estimation errors after removing detected low-quality signal segments.
Conclusions:
- The proposed unsupervised fECG SQA method effectively classifies signal quality without labeled data.
- This approach enhances the reliability of FHR estimation by improving fECG signal quality.
- The method offers a valuable tool for improving prenatal monitoring and fetal health assessment.

