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Current Advances in Technologies for Single Extracellular Vesicle Analysis and Its Clinical Applications in Cancer

Lei Qiu^1,2, Xingzhu Liu², Libo Zhu²

¹Department of Chemistry, College of Sciences, Shanghai University, Shanghai 200444, China.

|January 21, 2023

Abstract:

Extracellular vesicles (EVs) have been regarded as one of the most potential diagnostic biomarkers for different cancers, due to their unique physiological and pathological functions. However, it is still challenging to precisely analyze the contents and sources of EVs, due to their heterogeneity. Herein, we summarize the advances in technologies for a single EV analysis, which may provide new strategies to study the heterogeneity of EVs, as well as their cargo, more specifically. Furthermore, the applications of a single EV analysis on cancer early diagnosis are also discussed.

Keywords:

cancer diagnostic applications extracellular vesicles heterogeneity single particle

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Keywords:

cancer diagnostic applications extracellular vesicles heterogeneity single particle

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