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Updated: Aug 13, 2025

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
Structural Connectivity Reorganization Based on DTI after Cingulotomy in Obsessive-Compulsive Disorder
Sara Kierońska-Siwak1,2, Paweł Sokal1,2, Magdalena Jabłońska3
1Department of Neurosurgery and Neurology, Collegium Medicum, Nicolaus Copernicus University, 85-168 Bydgoszcz, Poland.
Abstract:
Bilateral cingulotomy is a procedure applied to patients with obsessive-compulsive disorder (OCD). This report presents the structural changes occurring within the forceps minor and arcuate fascicles nerve fibers after a successful bilateral anterior cingulotomy in the patient with refractory OCD. Cingulotomy mainly affects the values of FA, MD, and ADC in the treatment of the examined nerve bundles. This structural reorganization coexists with a good clinical effect. However, it is necessary to expand the study group and to investigate the correlation between the parameters of diffusion and anisotropy and the patient's clinical condition (Y-BOCS scale).
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