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Changes in Macular Thickness after Cataract Surgery in Patients with Open Angle Glaucoma
Giedre Pakuliene1, Neda Rylskyte1, Loreta Kuzmiene1
1Ophthalmology Department, Lithuanian University of Health Sciences, LT-50103 Kaunas, Lithuania.
Diagnostics (Basel, Switzerland)
|January 21, 2023
Summary
Cataract surgery in open-angle glaucoma patients led to decreased intraocular pressure (IOP) and increased macular thickness. Aqueous humor flare changes varied, with a notable increase in the control group post-surgery.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Cataract Surgery Outcomes
Background:
- Open-angle glaucoma (OAG) management often involves cataract surgery.
- Understanding the impact of cataract surgery on ocular parameters in OAG patients is crucial.
Purpose of the Study:
- To investigate changes in intraocular pressure (IOP), macular thickness, retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), and aqueous humor flare in OAG patients.
- To compare these changes before and 6 months after cataract surgery.
Main Methods:
- Prospective observational case-control study with age- and gender-matching.
- Inclusion of three groups: controlled OAG (OAGc), uncontrolled OAG (OAGu), and a control group.
- Utilized comprehensive ophthalmic evaluations including IOP measurement, OCT, and laser flare photometry.
Main Results:
- Intraocular pressure (IOP) decreased in all patient groups six months post-surgery.
- Macular thickness increased postoperatively across all groups.
- Aqueous humor flare was elevated preoperatively in OAGc patients and increased significantly in the control group post-surgery.
Conclusions:
- Post-cataract surgery IOP changes are inversely related to preoperative IOP levels.
- Macular thickness consistently increased six months after surgery in all evaluated groups.
- Aqueous humor flare showed no significant pre- to postoperative difference in OAG groups but increased in controls.
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