The Correlation between the Vascular Calcification Score of the Coronary Artery and the Abdominal Aorta in Patients

Trang Nguyen-Mai Huynh1, Fumikazu Yamazaki1,2, Izumi Kishimoto1

  • 1Department of Dermatology, Kansai Medical University, Osaka 573-1010, Japan.

Insights

Psoriasis patients show moderate correlation between coronary artery calcification score (CACS) and abdominal aortic calcification score (AACS). These scores may help predict coronary lesions, independent of psoriasis severity.

Area of Science:

  • Cardiology
  • Dermatology
  • Radiology

Background:

  • Psoriasis is an independent cardiovascular disease risk factor due to chronic inflammation.
  • Limited research exists on atherosclerosis progression in coronary arteries versus other major vessels in psoriasis patients.

Purpose of the Study:

  • To investigate the correlation and development of coronary artery calcification score (CACS) and abdominal aortic calcification score (AACS) in psoriasis patients.
  • To assess the predictive value of CACS and AACS for coronary artery lesions.

Main Methods:

  • Eighty-three psoriasis patients underwent coronary computed tomography angiography (CCTA) for CACS and abdominal computed tomography (AbCT) for AACS.
  • Clinical data, PASI scores, and blood samples were collected; medical histories were reviewed.
  • Linear regression analysis was used to determine associations between CACS and AACS.

Main Results:

  • A moderate correlation was observed between CACS and AACS.
  • Both scores reflected coronary plaque and stenosis characteristics identified by CCTA.
  • CACS was significantly higher in psoriatic arthritis patients, but AACS was not; neither score correlated with PASI score.

Conclusions:

  • CACS and AACS demonstrate a correlation in psoriasis patients.
  • Both CACS and AACS may serve as potential indicators for predicting coronary lesions identified via CCTA.

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