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Mesenterial histiocytic necrotizing lymphadenitis. Case report.

C Rudin1, R Wernli, M Rutishauser

  • 1Pediatric Clinic, University of Basel, Switzerland.

Helvetica Paediatrica Acta
|June 1, 1987
PubMed
Summary
This summary is machine-generated.

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A rare case of HNL (Hemorrhagic Necrotizing Lymphadenitis) presented atypically in a 14-year-old girl with abdominal symptoms. The unusual presentation and lack of granulocytic infiltration highlight diagnostic challenges.

Area of Science:

  • Pediatric Medicine
  • Pathology
  • Infectious Diseases

Background:

  • Hemorrhagic Necrotizing Lymphadenitis (HNL) is a rare condition.
  • Abdominal lymphadenopathy can present with diverse clinical symptoms.

Observation:

  • A 14-year-old female presented with fever, jaundice, vomiting, and abdominal pain, leading to laparotomy.
  • Enlarged, discolored lymph nodes were found in the mesentery.
  • Histologic diagnosis revealed HNL without granulocytic infiltration.

Findings:

  • The patient developed septic-toxic shock, respiratory insufficiency, and acute renal failure post-surgery.
  • The abdominal lymph node localization and lack of granulocytic infiltration were atypical for HNL.
  • No bacterial or viral pathogens were identified despite prior antibiotic treatment.

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Implications:

  • This case underscores the importance of considering HNL in pediatric abdominal emergencies with atypical presentations.
  • The diagnostic challenges presented by this case may inform future diagnostic strategies for HNL.
  • Further research into the etiology and pathogenesis of HNL is warranted, especially in cases lacking typical infectious markers.