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Related Experiment Video

Updated: Aug 13, 2025

Aptamer-Based Target Detection Facilitated by a 3-Stage G-Quadruplex Isothermal Exponential Amplification Reaction
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Aptamer-Based Technologies for Parasite Detection.

Noah Emerson Brosseau1,2, Isabelle Vallée1, Anne Mayer-Scholl3

  • 1UMR BIPAR, Anses, Laboratoire de Santé Animale, INRAE, Ecole Nationale Vétérinaire d'Alfort, 94700 Maisons-Alfort, France.

Sensors (Basel, Switzerland)
|January 21, 2023
PubMed
Summary
This summary is machine-generated.

Aptamer-based biosensors offer a promising new tool for detecting parasitic diseases. These advanced diagnostic tools provide high specificity and stability for monitoring parasite infections in animals and humans.

Keywords:
aptameraptasensorbiosensordetectiondiagnosticsparasite

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Area of Science:

  • Parasitology
  • Biotechnology
  • Biosensor technology

Background:

  • Parasitic diseases pose significant global health challenges for both humans and animals.
  • Current diagnostic and control methods face limitations despite technological advancements.
  • Aptamers are emerging as powerful alternatives to antibodies in diagnostics and therapeutics.

Purpose of the Study:

  • To review the application of aptamer-based biosensors for detecting parasites.
  • To summarize the mechanisms and performance of these biosensors.
  • To highlight aptamers as effective bioreceptors in biosensing.

Main Methods:

  • Review of scientific literature on aptamer-based biosensors for parasite detection.
  • Analysis of aptamer selection strategies and their integration into biosensor platforms.
  • Evaluation of biosensor performance metrics (specificity, affinity, sensitivity).

Main Results:

  • Aptamers demonstrate high specificity and affinity for detecting whole parasites and parasite proteins.
  • Various aptamer-based biosensors (electrochemical, fluorescence, optical) have been developed.
  • Aptamers offer advantages over traditional antibodies, including stability and reusability.

Conclusions:

  • Aptamer-based biosensors represent a significant advancement in parasitic disease detection.
  • These biosensors show great potential for improving diagnostics and control strategies.
  • Further development and application of aptamer biosensors are warranted for global health impact.