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Updated: Aug 13, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Survey of Explainable AI Techniques in Healthcare
Ahmad Chaddad1,2, Jihao Peng1, Jian Xu1
1School of Artificial Intelligence, Guilin University of Electronic Technology, Jinji Road, Guilin 541004, China.
Explainable AI (XAI) is crucial for making artificial intelligence (AI) trustworthy in healthcare. This survey reviews recent XAI techniques for medical imaging, offering guidelines for better AI interpretation.
Area of Science:
- Medical Imaging Analysis
- Artificial Intelligence in Healthcare
- Explainable Artificial Intelligence (XAI)
Background:
- Deep learning models are increasingly used in medical imaging and healthcare.
- AI decisions in medicine require transparency and interpretability, similar to human clinical judgment.
- The 'black-box' nature of deep learning hinders trust and adoption in critical medical applications.
Purpose of the Study:
- To survey recent Explainable AI (XAI) techniques applied to healthcare and medical imaging.
- To categorize XAI types and highlight algorithms enhancing interpretability in medical image analysis.
- To identify challenges and provide guidelines for developing better AI interpretations in clinical settings.
Main Methods:
- Comprehensive literature review of recent XAI techniques in medical imaging and healthcare.
- Categorization of XAI methods based on their approach to model interpretability.
- Analysis of algorithms used for increasing transparency in deep learning models for medical applications.
Main Results:
- Summary and categorization of current XAI techniques relevant to medical imaging.
- Identification of key algorithms that improve the interpretability of AI models in healthcare.
- Discussion of prevalent challenges and proposed solutions for XAI in medical contexts.
Conclusions:
- XAI is essential for the safe and effective integration of AI in medical decision-making.
- Guidelines are provided to improve the development and application of interpretable AI in medical imaging.
- Future research directions are outlined to advance XAI in clinical practice and medical image analysis.
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