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Updated: Aug 13, 2025
Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS
Published on: July 11, 2016
Re-identification and Characterization of Multidrug-Resistant Corynebacterium haemomassiliense-Like Organisms from
Hyeri Seok1, Ji-Young Choi2, Michidmaral Ganbold2
1Division of Infectious Diseases, Department of Medicine, Korea University Ansan Hospital, Korean University College of Medicine, Ansan, 15355, Republic of Korea.
Abstract:
Recently, non-diphtheriae Corynebacterium spp. have been increasingly reported in patients. In addition, several novel species of Corynebacterium isolated from humans. Here, we report two cases of human infections caused by Corynebacterium haemomassiliense-like organisms, which had not been identified at the species level by MALDI-TOF MS analysis. They were revealed to be closely related to C. haemomassiliense, a recently described species by three housekeeping genes (16S rRNA, rpoB, and gyrA) and phenotypic features. Both strains were multidrug-resistant but susceptible to vancomycin, meropenem, and linezolid. Our report suggests that human infections by the recently described Corynebacterium species may not be limited to a specific region, in addition to difficulty of classifying the genus Corynebacterium.
