Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

5.4K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
5.4K
Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

1.0K
Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
1.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effectiveness of adjuvant chemotherapy for patients who undergo radical cystectomy without neoadjuvant chemotherapy: A retrospective cohort study of 115 advanced bladder cancer patients with pathological lymph node classification.

International journal of urology : official journal of the Japanese Urological Association·2024
Same author

Efficacy and Safety Evaluation of Energy Devices in Bench Surgery for Pancreas Transplantation.

The Journal of surgical research·2024
Same author

Skeletal muscle mass during chemotherapy for haematological malignancies: a retrospective study.

BMJ supportive & palliative care·2024
Same author

Epidermoid cyst of the testis: A report of three cases.

Clinical case reports·2024
Same author

Simple pelvimetry predicts the pelvic manipulation time in robot-assisted low and ultra-low anterior resection for rectal cancer.

Surgery today·2024
Same author

<i>TP53</i> and/or <i>BRCA1</i> Mutations Based on CtDNA Analysis as Prognostic Biomarkers for Primary Triple-Negative Breast Cancer.

Cancers·2024

Related Experiment Video

Updated: Aug 13, 2025

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
17:06

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

26.3K

Dependence of apparent diffusion coefficient on slice position in magnetic resonance diffusion imaging.

Yasuo Takatsu1, Masafumi Nakamura2, Yuichi Suzuki3

  • 1Molecular Imaging, School of Medical Sciences, Fujita Health University, 1-98, Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan; Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, Ishikawa 920-0942, Japan.

Magnetic Resonance Imaging
|January 22, 2023
PubMed
Summary

Apparent diffusion coefficient (ADC) in MRI decreases with distance from the magnetic field center for both EPI- and TSE-DWI. Quantitative ADC evaluation requires caution when comparing sites along the long-axis direction.

Keywords:
Apparent diffusion coefficientDiffusion-weighted imageMagnetic resonance imagingSignal-to-noise ratioTurbo spin echo

More Related Videos

Diffusion Imaging in the Rat Cervical Spinal Cord
10:46

Diffusion Imaging in the Rat Cervical Spinal Cord

Published on: April 7, 2015

11.8K
Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

10.4K

Related Experiment Videos

Last Updated: Aug 13, 2025

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
17:06

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

26.3K
Diffusion Imaging in the Rat Cervical Spinal Cord
10:46

Diffusion Imaging in the Rat Cervical Spinal Cord

Published on: April 7, 2015

11.8K
Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

10.4K

Area of Science:

  • Magnetic Resonance Imaging (MRI)
  • Diffusion-Weighted Imaging (DWI)

Background:

  • Apparent diffusion coefficient (ADC) is a key metric in diffusion-weighted imaging (DWI) for assessing tissue microstructure.
  • Understanding the positional dependence of ADC in MRI is crucial for accurate quantitative analysis.

Purpose of the Study:

  • To assess the position dependence of the apparent diffusion coefficient (ADC) in magnetic resonance imaging (MRI) using echo-planar imaging (EPI) and turbo spin echo (TSE) diffusion-weighted imaging (DWI).
  • To evaluate the impact of magnetic field position on ADC measurements in phantom studies.

Main Methods:

  • Phantoms with pure water were placed at various positions relative to the magnetic field center.
  • Diffusion times for EPI-DWI and TSE-DWI were matched, and slice thickness was adjusted for comparable signal-to-noise ratio (SNR).
  • ADC, SNR, and flip angle (FA) were analyzed, with statistical comparisons using Wilcoxon signed-rank, Friedman, and Steel-Dwass tests.

Main Results:

  • ADC significantly decreased with increasing distance from the magnetic field center for both EPI-DWI and TSE-DWI.
  • TSE-ADC was consistently higher than EPI-ADC across all tested positions.
  • Both EPI-DWI and TSE-DWI showed significant position-dependent SNR variations.

Conclusions:

  • The apparent diffusion coefficient (ADC) is position-dependent in MRI, decreasing as the slice position moves away from the magnetic field center.
  • Care must be exercised when comparing and quantitatively evaluating ADC values obtained at different positions along the long-axis direction.