Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Psychosurgery01:30

Psychosurgery

91
Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
91

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Atypical Histopathological Findings in an Epilepsy Surgery Case of Sturge-Weber Syndrome With Coexisting Developmental Venous Anomaly.

Neuropathology : official journal of the Japanese Society of Neuropathology·2026
Same author

Late-onset Vitamin B6-dependent epilepsy caused by compound heterozygous pathogenic PLPBP variants.

European journal of medical genetics·2025
Same author

Epileptic drop attacks: More than just atonic seizures.

Epilepsia open·2025
Same author

WONOEP appraisal: The role of glial cells in focal malformations associated with early onset epilepsies.

Epilepsia·2024
Same author

Intravenous perampanel as an alternative to the oral formulations in Japanese patients with epilepsy.

Epilepsia open·2023
Same author

Temporal Lobe Surgery for Epilepsy in a Resource-Limited Vietnamese Cohort.

World neurosurgery·2023

Related Experiment Video

Updated: Aug 13, 2025

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE
06:04

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE

Published on: August 16, 2024

978

[Current Position of Callosotomy].

Tomonori Ono1

  • 1Epilepsy Center, Department of Neurosurgery, National Hospital Organization Nagasaki Medical Center.

No Shinkei Geka. Neurological Surgery
|January 22, 2023
PubMed
Summary

Callosotomy surgery is a valuable treatment for drug-resistant epilepsy, especially for generalized seizures and drop attacks. While disconnection syndrome can occur, its effects are usually temporary and outweighed by seizure improvement.

Area of Science:

  • Neurosurgery
  • Epileptology

Context:

  • Callosotomy is a surgical procedure used for medically refractory epilepsy.
  • Indications include generalized or unknown-onset seizures, bilateral epileptiform discharges, and specific epilepsy syndromes like Lennox-Gastaut syndrome.

Purpose:

  • To review the efficacy and safety of callosotomy as a surgical treatment for epilepsy.
  • To discuss surgical techniques, patient selection, and outcomes.

Summary:

  • Callosotomy is effective for patients with generalized or unknown-onset seizures, particularly those experiencing drop attacks.
  • One-stage total callosal section shows favorable outcomes in pediatric patients.
  • Anterior callosotomy is recommended for older children and adults, with staged complete sections considered if needed.

More Related Videos

Neuronavigation and Laparoscopy Guided Ventriculoperitoneal Shunt Insertion for the Treatment of Hydrocephalus
14:59

Neuronavigation and Laparoscopy Guided Ventriculoperitoneal Shunt Insertion for the Treatment of Hydrocephalus

Published on: October 14, 2022

7.5K
Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery
12:04

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Published on: January 6, 2011

13.1K

Related Experiment Videos

Last Updated: Aug 13, 2025

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE
06:04

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE

Published on: August 16, 2024

978
Neuronavigation and Laparoscopy Guided Ventriculoperitoneal Shunt Insertion for the Treatment of Hydrocephalus
14:59

Neuronavigation and Laparoscopy Guided Ventriculoperitoneal Shunt Insertion for the Treatment of Hydrocephalus

Published on: October 14, 2022

7.5K
Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery
12:04

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Published on: January 6, 2011

13.1K

Impact:

  • Surgical techniques are advancing, with less invasive methods being explored.
  • Disconnection syndrome is an unavoidable complication but is typically transient and often outweighed by seizure symptom improvement, especially in children due to brain plasticity.