Related Experiment Video
Updated: Jul 25, 2026

05:53
Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
Rapid prototyping of database systems in human genetics data collection
1Computer and Information Science Department, Indiana University, Purdue University at Indianapolis 46223.
Journal of Medical Systems
|June 1, 1987
Summary
Developing database applications for human genetics data, including family pedigrees, presents challenges. MEGADATS-4 software offers rapid prototyping and stand-alone application development with minimal programming.
Area of Science:
- Bioinformatics
- Database Management
- Human Genetics
Background:
- Developing database applications for human genetics data collection, encompassing individual and family pedigree information, faces significant challenges.
- The need for efficient data management is crucial for genetic research and clinical applications.
Purpose of the Study:
- To examine the problems in developing small and large database application systems for human genetics data.
- To evaluate the capabilities of MEGADATS-4 software in addressing these challenges through rapid prototyping and stand-alone application generation.
Main Methods:
- Analysis of database development challenges in human genetics.
- Examination of MEGADATS-4 software features for rapid prototyping.
- Assessment of MEGADATS-4's ability to produce stand-alone applications.
Main Results:
- Identification of key issues in creating robust database systems for genetic data.
- Demonstration of MEGADATS-4's effectiveness in streamlining application development.
- Validation of MEGADATS-4's utility for generating independent applications.
Conclusions:
- MEGADATS-4 provides effective solutions for the rapid development of database applications in human genetics.
- The software facilitates the creation of stand-alone applications, simplifying deployment and accessibility for genetic data management.
Related Concept Videos
Evolutionary Relationships through Genome Comparisons
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
Genetic Screens
Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...

