Case Report: Rhabdomyolysis in aneurysmal subarachnoid hemorrhage: A rare case with implications for management

Gang Liao1, Kang Chen1, Jiang Xu1

  • 1Department of Neurosurgery, First Affiliated Hospital of Nanchang University, Nanchang City, China.

Frontiers in Surgery
|January 23, 2023
PubMed
Abstract

Insights

Rhabdomyolysis, a condition causing muscle breakdown, can occur after intracranial aneurysm surgery. Early detection of elevated creatine phosphokinase (CK) and prompt treatment are crucial for patient recovery and preventing kidney damage.

Area of Science:

  • Neurosurgery
  • Nephrology
  • Intensive Care Medicine

Background:

  • Rhabdomyolysis is a rare but serious complication following surgical procedures.
  • Intracranial aneurysm surgery presents unique challenges and potential risks, including muscle injury.
  • This report focuses on a specific case to highlight the occurrence of rhabdomyolysis post-neurosurgery.

Observation:

  • A 59-year-old male presented with coma, fever, and dark, soy sauce-colored urine post-intracranial aneurysm clipping.
  • Laboratory results revealed impaired liver and kidney function, with significantly elevated creatine phosphokinase (CK) and CK-isoenzyme (CK-MB) levels.
  • These clinical and biochemical findings were indicative of rhabdomyolysis.

Findings:

  • The patient was diagnosed with rhabdomyolysis secondary to intracranial aneurysm surgery.
  • Immediate interventions included intravenous fluid resuscitation, urine alkalization, and ultimately, hemodialysis.
  • The patient demonstrated a positive response to treatment and was safely discharged.

Implications:

  • Postoperative monitoring for elevated CK/CK-MB levels and changes in urine color is essential for early rhabdomyolysis detection.
  • Prompt and aggressive management of rhabdomyolysis is critical to prevent acute kidney injury and other severe complications.
  • This case underscores the importance of recognizing and managing rhabdomyolysis in the context of neurosurgical interventions.

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