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Updated: Aug 13, 2025

A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice
Published on: April 17, 2019
Ga-68 DOTATATE PET/CT in a patient with Zollinger-Ellison syndrome
Migara Jayasekera1, Stephen Sartin1, Peeyush Bhargava1
1Department of Radiology, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555, USA.
Abstract:
This case report follows a 70-year-old male patient with Zollinger-Ellison syndrome undergoing computed tomography (CT) for weight loss and surveillance of bilateral adrenal nodules. Incidentally, diffuse gastric and duodenal wall thickening was noted on CT. The patient underwent esophagogastroduodenoscopy with biopsy results showing well-differentiated neuroendocrine tumors (NET) in the stomach and duodenum. Subsequent imaging with gallium-68 DOTATATE PET/CT showed intense tracer uptake in the stomach and proximal duodenum with liver and regional nodal metastases around the superior mesenteric artery. This case outlines the utility of Ga-68 DOTATATE PET/CT in diagnosing, localizing, and staging NET such as gastrinomas.
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