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One-year survival and prognostic factors for survival among stroke patients: The PROVE-stroke study

Mahshid Givi1, Negin Badihian2, Marzieh Taheri3

  • 1Nursing and Midwifery Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Journal of Research in Medical Sciences : the Official Journal of Isfahan University of Medical Sciences
|January 23, 2023
PubMed

Insights

Stroke survival rates in Iran show that 72.1% of patients lived one year post-stroke. Key predictors included age, diabetes, prior stroke, and hospital complications like hemorrhage and sepsis.

Area of Science:

  • Neurology
  • Public Health
  • Epidemiology

Background:

  • Stroke incidence and outcomes vary globally, with limited data from the Middle East.
  • Understanding regional stroke patterns is crucial for targeted public health interventions.

Purpose of the Study:

  • To determine 1-year survival rates among stroke patients in Central Iran.
  • To identify prognostic factors influencing stroke survival in this specific population.

Main Methods:

  • An observational analytical study using the PROVE-Stroke database.
  • Reviewed records of 1703 patients admitted for stroke in Isfahan, Iran, between 2015-2016.
  • Collected data on demographics, clinical details, comorbidities, and 1-year survival status.

Main Results:

  • Out of 1345 patients, 970 (72.1%) survived one year, with a mean survival time of 277.33 days.
  • Ischemic stroke (84.8%) was more common than hemorrhagic stroke (15.0%).
  • Significant predictors of mortality included advanced age, diabetes, history of stroke/TIA, warfarin use, hospital-acquired hemorrhage, sepsis, hydrocephalus, and a modified Rankin Scale score of ≥3 at discharge.

Conclusions:

  • Identified both unmodifiable (age, diabetes, prior stroke, mRS) and modifiable (hospital complications) predictors of 1-year stroke survival.
  • Highlights the importance of managing hospital-acquired complications to reduce stroke mortality.
Abstract

Keywords:
Hemorrhagic strokeIranischemic strokeprognosissurvival analysis

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