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Quantification of Vascular Parameters in Whole Mount Retinas of Mice with Non-Proliferative and Proliferative Retinopathies
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Segmentation of retinal vessels based on MRANet
Sanli Yi1, Yanrong Wei1, Gang Zhang1
1School of Information Engineering and Automation, Kunming University of Science and Technology, Kunming 650500, Yunnan, China.
Heliyon
|January 23, 2023
Summary
This study introduces a novel Multi-Scale Residual Attention Network (MRANet) for improved retinal vessel segmentation. The MRANet enhances diagnostic accuracy by effectively segmenting fine capillaries and reducing noise interference.
Area of Science:
- Ophthalmology
- Medical Imaging
- Computer Vision
Background:
- Retinal vessel segmentation is vital for diagnosing eye diseases.
- Challenges include segmenting fine capillaries and handling noise.
Purpose of the Study:
- To develop an improved method for retinal vessel segmentation.
- To address limitations of existing methods in capillary segmentation and noise resistance.
Main Methods:
- Proposed a Multi-Scale Residual Attention Network (MRANet) based on U-Net.
- Introduced Multi-Level Feature Fusion (MLF) block for effective information collection.
- Utilized attention blocks for feature weighting and DropBlock layer to reduce parameters and overfitting.
Main Results:
- Achieved high accuracy (0.9698 on DRIVE, 0.9755 on CHASE_DB1) and AUC (0.9899 on DRIVE, 0.9893 on CHASE_DB1).
- Demonstrated superior segmentation compared to other methods.
- Ensured continuity and completeness in blood vessel segmentation.
Conclusions:
- MRANet significantly improves retinal vessel segmentation accuracy and robustness.
- The proposed network effectively segments fine vessels and reduces noise.
- This method holds promise for enhanced computer-aided diagnosis of eye disorders.

