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An algorithm for cognitive fusion targeted tumor puncture based on 3-D mathematical modelling.
Yong Luo1, Junjie Ren2, Jun Long3
1Department of Urology, Daping Hospital, Army Medical University, Chongqing, 400042, China.
Heliyon
|January 23, 2023
Summary
This study introduces a mathematical model for precise percutaneous tumor puncture, significantly improving accuracy and reducing patient discomfort. The innovative approach enhances diagnostic and treatment outcomes for tumors.
Area of Science:
- Medical Imaging and Interventional Radiology
- Computational Biology and Mathematical Modeling
Background:
- Percutaneous tumor puncture is crucial for diagnosis and treatment but often relies on empirical methods, limiting accuracy and increasing complication risks.
- Current techniques lack quantitative precision, hindering optimal outcomes in tumor interventions.
- Improving percutaneous tumor puncture accuracy and safety remains a significant clinical challenge.
Purpose of the Study:
- To develop and validate a mathematical model for precise, quantitative percutaneous tumor puncture.
- To enhance the accuracy, efficiency, and safety of tumor diagnosis and treatment procedures.
- To reduce patient pain and improve overall clinical outcomes.
Main Methods:
- Mathematical modeling was employed to construct optimal tumor puncture paths and determine needle entry angles.
- Clinical data from CT and ultrasound imaging were extracted to calculate personalized puncture deviation angles and schemes.
- Targeted punctures were performed under B-ultrasound guidance using the developed model.
Main Results:
- The mathematical model significantly increased puncture accuracy by approximately 30% compared to conventional methods.
- Puncture procedures were more efficient, reducing the number of punctures by 50% and operation time by 20%.
- The model enhanced doctor satisfaction by 20% and reduced patient discomfort by 25%.
Conclusions:
- A novel mathematical model integrating imaging data and clinical parameters enables accurate and personalized percutaneous tumor puncture.
- The model demonstrably improves puncture effectiveness, patient safety, and reduces invasiveness.
- This approach shows significant potential for widespread clinical application in tumor interventions.

