Achieving immunization agenda 2030 coverage targets for 14 pathogens: Projected product and immunization delivery...

Area of Science:

• Global Health
• Health Economics
• Vaccinology

Background:

• The Immunization Agenda 2030 (IA2030) aims to achieve global immunization goals.
• Understanding future investment needs is critical for IA2030 success.

Purpose of the Study:

• To estimate the global and regional economic resources required for IA2030 from 2021 to 2030.
• To assess immunization program costs, including routine and non-routine expenditures.

Main Methods:

• Economic modeling to estimate costs for 194 WHO member countries.
• Inclusion of 14 vaccine-preventable diseases.
• Scenario and sensitivity analyses for cost uncertainty.

Main Results:

• Total estimated cost for immunization programs: $269.8 billion (95% CI: $247.1 - $311.8).
• Routine vaccine and delivery costs constitute the majority of expenditures.
• Incremental costs for achieving IA2030 goals are estimated at $89.9 billion, with upper-middle income countries needing the largest increase.

Conclusions:

• Immunization program costs are projected to rise significantly this decade.
• Resource mobilization and increased investment are essential for achieving IA2030 coverage.
• Sustainable immunization programs depend on strategic financial planning and contributions from governments and donors.