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Related Experiment Videos

Sequential hepatobiliary scintigraphy demonstrating apparent transient biliary obstruction.

A F Jacobson1, E B Cronin, B L Holman

  • 1Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts 02115.

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|November 1, 1987
PubMed
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Sequential hepatobiliary scintigraphy revealed transient biliary obstruction in acute acalculous cholecystitis. Reinjection with technetium-99m diisopropyliminodiacetic acid ([99mTc]DISIDA) clarified hepatobiliary function.

Area of Science:

  • Hepatobiliary imaging
  • Diagnostic nuclear medicine

Background:

  • Acute acalculous cholecystitis presents diagnostic challenges.
  • Hepatobiliary scintigraphy is crucial for evaluating gallbladder and biliary tract function.

Observation:

  • A patient with suspected acute cholecystitis showed nonvisualization of the gallbladder and delayed intestinal activity on initial [99mTc]DISIDA imaging.
  • A subsequent [99mTc]DISIDA injection visualized the gallbladder and bowel within 75 minutes.

Findings:

  • The surgical findings confirmed acute and chronic cholecystitis without choledocholithiasis.
  • Transient biliary obstruction can mimic partial obstruction on delayed scintigraphic images due to intrahepatic cholestasis.

Implications:

Related Experiment Videos

  • Sequential imaging with reinjection of [99mTc]DISIDA may be necessary for accurate assessment of hepatobiliary function in select cases.
  • This case highlights the importance of considering transient obstruction in interpreting hepatobiliary scintigraphy findings.