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Updated: Aug 13, 2025

Depolymerizable Olefinic Polymers Based on Fused-Ring Cyclooctene Monomers
Published on: December 16, 2022
Recent Advances in Drug Release, Sensing, and Cellular Uptake of Ring-Opening Metathesis Polymerization (ROMP)
Upendar Reddy Gandra1,2, Santhosh Kumar Podiyanachari1, Hassan S Bazzi1,3
1Division of Arts and Sciences, Texas A&M University at Qatar, P.O. Box 23874, Doha 23874, Qatar.
Abstract:
The synthesis and applications of ring-opening metathesis polymerization (ROMP) derived poly(olefins) have emerged as an exciting area of great interest in the field of biomaterials science. The major focus of this mini-review is to present recent advances in the synthesis of functional materials using ROMP-derived poly(olefins) utilized for drug release, sensing, and cellular uptake in the past seven years (2015-2022). This review reveals that materials synthesized by ROMP-derived well-defined functional poly(olefins) stand to be highly promising systems for medical as well as biological studies. Thus, this review may prove to be beneficial for the design and development of new smart and flexible-functionality ROMP-based polymeric materials for various biological applications.
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