An Unusual Stomach Tumour: Plexiform Angiomyxoid Fibroma Stomach-A Case Report

Sharath K Krishnan1, Ravindran Chirukandath1, Togy Zachariah2

  • 1Department of General Surgery, Government Medical College, Thrissur, 680596 Kerala India.

Insights

Plexiform angiomyxoid myofibroblast tumour (PAMT) is a rare gastric mesenchymal tumor. This case highlights a large PAMT requiring multi-visceral resection, emphasizing its rarity and challenging surgical management.

Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Pathology

Background:

  • Plexiform angiomyxoid myofibroblast tumour (PAMT) is an exceptionally rare mesenchymal neoplasm of the stomach.
  • Fewer than 50 cases have been documented, characterized by spindle cells with myofibroblast features.

Purpose of the Study:

  • To report a rare case of PAMT in the gastric body.
  • To discuss the diagnostic and surgical challenges posed by this rare entity.

Main Methods:

  • Case presentation of a 70-year-old woman with upper abdominal pain and dyspepsia.
  • Diagnostic workup included esophagogastroduodenoscopy (OGD) and CT scan.
  • Surgical management involved multi-visceral resection.

Main Results:

  • OGD revealed a polypoidal lesion with ulceration; biopsy suggested PAMT.
  • CT scan demonstrated a large tumor (10x8 cm) with pancreatic and splenic involvement.
  • Multi-visceral resection resulted in a favorable outcome.

Conclusions:

  • PAMT is a rare gastric mesenchymal tumor with a unique histology, distinct from GIST.
  • While typically benign, PAMT can exhibit infiltrative behavior and require extensive surgical intervention.
  • This case underscores the importance of recognizing PAMT and the technical complexities of its surgical resection.