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ExCYT: A Graphical User Interface for Streamlining Analysis of High-Dimensional Cytometry Data
Published on: January 16, 2019
Cistrome Explorer: an interactive visual analysis tool for large-scale epigenomic data
Sehi L'Yi1, Mark S Keller1, Ariaki Dandawate2
1Department of Biomedical Informatics, Harvard Medical School.
Summary:
The regulation of genes by cis-regulatory elements (CREs) is complex and differs between cell types. Visual analysis of large collections of chromatin profiles across diverse cell types, integrated with computational methods, can reveal meaningful biological insights. We developed Cistrome Explorer, a web-based interactive visual analytics tool for exploring thousands of chromatin profiles in diverse cell types. Integrated with the Cistrome Data Browser database which contains thousands of ChIP-seq, DNase-seq and ATAC-seq samples, Cistrome Explorer enables the discovery of patterns of CREs across cell types and the identification of transcription factor binding underlying these patterns.
Availability And Implementation:
Cistrome Explorer and its source code are available at http://cisvis.gehlenborglab.org/ and released under the MIT License. Documentation can be accessed via http://cisvis.gehlenborglab.org/docs/.
Supplementary Information:
Supplementary data are available at Bioinformatics online.
